|The following testimonial
appeared in the December 1999 issue of Neuropathy News,
a patient newsletter.
"My local [compounding
pharmacist] has created a cream to help alleviate the
pain of foot neuropathy. It reduces the burning and sharp,
needle-like pain. All you need is a very thin coat. The
directions call for using it four times a day, but I find
it particularly helpful at night. [The formulation contains]
2% amitriptyline and 2% baclofen in a transdermal gel."
have the unique training and ability to create medications
that address the individual needs of patients. One of
the most helpful products they use are transdermal gels
that allow for the passage of medication directly through
the tissue into the area of pain. Many of the medications
typically prescribed for neuropathy patients such as
amitriptyline, lidocaine, mexilitene, ketamine and [gabapentin]
can cause significant side effects when taken orally.
Transdermal gel minimizes systemic side effects and
maximizes local pain relief. Compounding pharmacists
have many resources that offer relief from neuropathic
Diabetes Interviews, January 2000,
Neil A. Burrell, DPM, CDE, of Beaumont, Texas, writes
"We have a very high success rate
using amitriptyline and baclofen mixed in a gel component.
This compound is applied to the feet three times per
day, and offers immediate relief... [For] recalcitrant
neuropathic pain, many times we use a combination of
tramadol, gabapentin and amitriptyline."